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Comentario sobre "Ganancia de función específica para humanos en un potenciador del desarrollo"
Laurent Duret1, Nicolas Galtier
1Université de Lyon, Université Lyon 1, CNRS, UMR5558, Laboratoire de Biométrie et Biologie Evolutive, F-69622, Villeurbanne, France. duret@biomserv.univ-lyon1.fr
Science (New York, N.Y.)
|February 7, 2009
Resumen
La secuencia específica para humanos HACNS1 muestra evolución neutral, no selección positiva. Sus cambios funcionales probablemente sean el resultado de la conversión genética sesgada, no de la adaptación.
Área de la Ciencia:
- Biología evolutiva Biología evolutiva.
- Genética humana Genética humana es la genética humana.
- Evolución molecular de la evolución molecular.
Sus antecedentes:
- Anteriormente se propuso que la secuencia no codificante conservada HACNS1 estuviera bajo selección positiva, impulsando la adaptación humana.
- Esta hipótesis se basó en patrones de sustitución observados en HACNS1.
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