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El transporte bidireccional de aminoácidos regula la mTOR y la autofagia

Paul Nicklin1, Philip Bergman, Bailin Zhang

  • 1Respiratory Diseases Area, Novartis Institutes for BioMedical Research, Novartis Horsham Research Centre, West Sussex, UK.

Cell
|February 11, 2009
PubMed
Resumen

El transporte de aminoácidos a las células, específicamente la captación y el eflujo de L-glutamina, es crucial para activar la vía de la rapamicina (mTOR) en mamíferos, controlando el crecimiento celular y la síntesis de proteínas.

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