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Manifestaciones cardiopulmonares de la esquistosomiasis hepática esplénica
Monica Lapa1, Bruno Dias, Carlos Jardim
1Pulmonary Hypertension Group, Pulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Circulation
|March 11, 2009
Resumen
La esquistosomiasis hepatosfénica es una causa común de hipertensión pulmonar en todo el mundo. La ecocardiografía es una herramienta de detección útil, pero se necesita un cateterismo del corazón derecho para el diagnóstico.
Área de la Ciencia:
- La medicina tropical es una medicina tropical.
- Cardiología Cardiología.
- Enfermedades infecciosas Enfermedades infecciosas.
Sus antecedentes:
- La esquistosomiasis afecta a más de 200 millones de personas en todo el mundo.
- La hipertensión pulmonar es una complicación conocida de la esquistosomiasis, especialmente la forma hepatosplénica.
- La prevalencia de la hipertensión pulmonar en este grupo específico de pacientes requiere más investigación.
Objetivo del estudio:
- Para determinar la prevalencia de la hipertensión pulmonar en pacientes con esquistosomiasis hepatosplénica.
Principales métodos:
- La ecocardiografía se utilizó para detectar la hipertensión pulmonar (presión sistólica de la arteria pulmonar >40 mm Hg).
- Los pacientes con lecturas elevadas se sometieron al cateterismo del corazón derecho para la evaluación hemodinámica invasiva.
- Se calcularon las tasas de prevalencia para la presión arterial pulmonar sistólica elevada y la hipertensión pulmonar confirmada.
Principales resultados:
- La ecocardiografía reveló una presión arterial pulmonar sistólica elevada en el 18,5% de los pacientes.
- El cateterismo del corazón derecho confirmó la hipertensión pulmonar en el 7,7% de los pacientes.
- La hipertensión pulmonar precapillar (arterial) fue diagnosticada en el 4,6% de la cohorte del estudio.
Conclusiones:
- La ecocardiografía sirve como una herramienta de detección eficaz para la hipertensión pulmonar en pacientes con esquistosomiasis.
- El monitoreo hemodinámico invasivo es esencial para un diagnóstico preciso.
- La esquistosomiasis hepatosplénica es un contribuyente significativo a la carga global de la hipertensión pulmonar, lo que justifica una mayor investigación sobre tratamientos dirigidos.
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