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Cicloadiciones inter e intramoleculares [4 + 3] que utilizan silanos de enol epóxi como precursores funcionalizados

Wing Ki Chung1, Sze Kui Lam, Brian Lo

  • 1Department of Chemistry and the Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, PR China.

Journal of the American Chemical Society
|March 14, 2009
PubMed
Resumen

En este estudio se introducen los silanos de enol epoxi como precursores de los cationes oxyallyl en las cicloadiciones [4+3]. Estas reacciones producen eficientemente complejos conductos ciclóricos hidroxilados con alta estereoselectividad, incluso a partir de materiales de partida enantioméricamente puros.

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