Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

Phagocytosis of Apoptotic Cells01:17

Phagocytosis of Apoptotic Cells

Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or  immature dendritic cells. Non-professional phagocytes such as  epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes. 
Normal cells contain receptors that prevent them from being recognized by phagocytes.
Necrosis01:16

Necrosis

Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Free-falling Bodies: Introduction01:07

Free-falling Bodies: Introduction

All objects, neglecting air resistance, fall with the same acceleration towards the Earth's center due to the force exerted by the Earth's gravity. This experimentally determined fact is unexpected because we are so accustomed to the effects of air resistance and friction that we expect light objects to fall slower than heavier ones. People believed that a heavier object had a greater acceleration when falling until Galileo Galilei (1564–1642) proved otherwise. We now know this is not the case.
Free-falling Bodies: Example01:05

Free-falling Bodies: Example

An object falling without any air resistance under the influence of gravitational force is said to be in free-fall. For free-falling bodies, the acceleration due to gravity is constant, irrespective of their mass. Free-fall is experienced not only by objects falling downward, but also by all objects whose motion is influenced by gravitational force alone. The dynamics of free-fall motion can be calculated using kinematic equations of motion, since free-fall acceleration is constant.
The...
Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Cellular Injury IlI: Cellular Death01:11

Cellular Injury IlI: Cellular Death

Cell death is the irreversible loss of cellular structure and function, representing the final stage of severe injury. It plays a key role in both normal physiology and disease.Types of Cell DeathThe two main types are necrosis and apoptosis, though others like necroptosis and pyroptosis also exist.Necrosis:Necrosis is an unregulated form of cell death caused by severe injury such as trauma, toxins, or ischemia. It is characterized by cell swelling, membrane loss, rupture, and leakage of...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Theory of mind and executive functions in sighted children of blind parents.

Frontiers in psychology·2026
Same author

Fibroblasts of disparate developmental origins harbor anatomically variant scarring potential.

Cell·2026
Same author

Is transition from failing to passing False Belief Task reflected in the social brain? Insights from an fNIRS study with preschoolers.

Social neuroscience·2026
Same author

The craniofacial shape of modern humans embodies genomic signatures of evolution, diversity, and clinical conditions.

bioRxiv : the preprint server for biology·2026
Same author

Genetic and chromatin regulation of Pvt1 monoallelic expression.

Cell reports·2025
Same author

A human-specific regulatory mechanism revealed in a pre-implantation model.

Nature·2025
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
Ver todos los artículos relacionados
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Jun 11, 2026

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis
12:55

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis

Published on: February 16, 2015

Los inmortales caídos.

Tomek Swigut1, Joanna Wysocka

  • 1Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA.

Cell
|April 22, 2009
PubMed
Resumen
Este resumen es generado por máquina.

La memoria de expresión génica de las células somáticas se restablece en la línea germinal a través de modificaciones de la cromatina. La histona demetilasa Lsd1/Spr-5 puede mantener la estabilidad epigenética de las células germinales y la viabilidad a través de generaciones en gusanos.

Más Videos Relacionados

Isolation and Immortalization of Patient-derived Cell Lines from Muscle Biopsy for Disease Modeling
11:26

Isolation and Immortalization of Patient-derived Cell Lines from Muscle Biopsy for Disease Modeling

Published on: January 18, 2015

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells
12:17

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells

Published on: January 2, 2016

Videos de Experimentos Relacionados

Last Updated: Jun 11, 2026

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis
12:55

Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis

Published on: February 16, 2015

Isolation and Immortalization of Patient-derived Cell Lines from Muscle Biopsy for Disease Modeling
11:26

Isolation and Immortalization of Patient-derived Cell Lines from Muscle Biopsy for Disease Modeling

Published on: January 18, 2015

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells
12:17

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells

Published on: January 2, 2016

Área de la Ciencia:

  • La epigenética es la epigenética.
  • Biología del desarrollo Biología del desarrollo.
  • Genética La genética.

Sus antecedentes:

  • Las células somáticas normalmente borran la memoria epigenética durante la reprogramación de la línea germinal.
  • Este proceso implica una modificación significativa de la cromatina.
  • El mantenimiento de la estabilidad epigenética en las células germinales es crucial para el éxito reproductivo.

Objetivo del estudio:

  • Para investigar el papel de la histona demetilasa Lsd1/Spr-5 en el restablecimiento epigenético de la línea germinal en gusanos.
  • Comprender cómo Lsd1/Spr-5 contribuye a mantener la estabilidad epigenética y la viabilidad de las células germinales.

Principales métodos:

  • El estudio probablemente involucró análisis genético y técnicas moleculares en el organismo modelo *C. elegans*.
  • Investigando la función de Lsd1/Spr-5 en las células germinales.
  • Evaluar el impacto en las modificaciones de la cromatina y la herencia epigenética.

Principales resultados:

  • Katz y otros. (2009) demuestran que Lsd1/Spr-5 juega un papel en el restablecimiento de la línea germinal de la expresión génica somática.
  • Esta histona desmetilasa parece estar involucrada en la prevención de la disminución de la estabilidad epigenética de las células germinales.
  • Los hallazgos sugieren que Lsd1/Spr-5 es importante para garantizar la viabilidad de las células germinales a través de las generaciones.

Conclusiones:

  • La histona demetilasa Lsd1/Spr-5 está implicada en el proceso crucial de la reprogramación epigenética de la línea germinal.
  • La actividad Lsd1/Spr-5 es esencial para mantener la integridad epigenética de las células germinales.
  • Este mecanismo asegura la herencia estable de la información epigenética, vital para el éxito reproductivo.