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Updated: Jun 23, 2026

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
11:27

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

Las estructuras cristalinas de la ciclohexanona monooxigenasa revelan movimientos complejos de dominio y un cofactor

I Ahmad Mirza1, Brahm J Yachnin, Shaozhao Wang

  • 1Department of Biochemistry, McGill University, 3649 Prom Sir William Osler, Bellini Pavilion, Room 466, Montreal, QC, Canada H3G 0B1.

Journal of the American Chemical Society
|April 24, 2009
PubMed
Resumen

La ciclohexanona monooxigenasa (CHMO, por sus siglas en inglés) cataliza la oxidación de Baeyer-Villiger. El análisis estructural revela cambios de dominio y movimientos de bucle cruciales para el posicionamiento del cofactor y la unión del sustrato, ofreciendo información mecanicista sobre esta reacción enzimática.

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