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Updated: Jun 23, 2026

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La aciltransferasa/decarboxilasa bifuncional LnmK como el eslabón perdido para la beta-alquilación en la biosíntesis

Tao Liu1, Yong Huang, Ben Shen

  • 1Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53705-2222, USA.

Journal of the American Chemical Society
|May 2, 2009
PubMed
Resumen

Los investigadores identificaron LnmK, una enzima crucial para la biosíntesis del policetido. Esta enzima bifuncional aciltransferasa/decarboxilasa (AT/DC) genera la proteína transportadora propionil-acil (ACP), lo que explica el origen de las ramas beta-etil en los productos naturales.

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