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Updated: Jun 22, 2026

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture
09:37

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture

Published on: May 2, 2019

Formación de disulfuro en el ER y las mitocondrias: dos soluciones a un proceso común

Jan Riemer1, Neil Bulleid, Johannes M Herrmann

  • 1Cell Biology, University of Kaiserslautern, Erwin Schrödinger Strasse 13, 67663 Kaiserslautern, Germany.

Science (New York, N.Y.)
|June 6, 2009
PubMed
Resumen

Las células eucariotas poseen dos compartimentos oxidantes distintos, el retículo endoplasmático (ER) y las mitocondrias, que catalizan la formación de enlaces disulfuro de proteínas. Estos sistemas, cruciales para el plegamiento y la translocación de proteínas, tienen diferentes orígenes y mecanismos evolutivos.

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