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Updated: Jun 21, 2026

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

Mutación in vitro de los análogos lantibióticos que contienen aminoácidos no proteinogénicos

Matthew R Levengood1, Patrick J Knerr, Trent J Oman

  • 1Howard Hughes Medical Institute and Roger Adams Laboratory, Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA.

Journal of the American Chemical Society
|August 7, 2009
PubMed
Resumen

Los investigadores crearon nuevos análogos lantibióticos utilizando aminoácidos no proteinogénicos. Dos análogos, Trp19Nal y Phe23hPhe, mostraron una mayor actividad antimicrobiana contra Lactococcus lactis HP.

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