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Asociación entre la oftalmopatía de Graves y el tabaquismo
B Shine1, P Fells, O M Edwards
1Institute of Ophthalmology, London, UK.
Lancet (London, England)
|May 26, 1990
Resumen
Los fumadores son más comunes en pacientes con Graves.
Área de la Ciencia:
- Endocrinología Endocrinología.
- Oftalmología Oftalmología.
- Salud Pública La salud pública.
Sus antecedentes:
- La enfermedad de Graves es un trastorno autoinmune que afecta a la glándula tiroides.
- La oftalmopatía de Graves es una manifestación común de la enfermedad de Graves, que causa complicaciones oculares.
- Fumar es un factor de riesgo conocido para varias afecciones de salud, pero su papel específico en la enfermedad de Graves y la oftalmopatía requiere una mayor aclaración.
Objetivo del estudio:
- Para investigar la asociación entre el tabaquismo y la presencia y gravedad de la oftalmopatía de Graves.
- Para comparar la prevalencia del tabaquismo en pacientes con enfermedad de Graves (con y sin oftalmopatía) y en individuos de control.
Principales métodos:
- Se realizó una encuesta postal entre pacientes diagnosticados con la enfermedad de Graves.
- Los participantes fueron interrogados sobre su historial de tabaquismo.
- El estado y la intensidad del tabaquismo se compararon entre los grupos con y sin oftalmopatía, y con un grupo de control.
Principales resultados:
- Se observó una proporción significativamente mayor de fumadores en el grupo de oftalmopatía de Graves en comparación con el grupo de solo tirotoxicosis de Graves y el grupo de control.
- Los pacientes que exhibieron signos oftalmopáticos severos demostraron un consumo de tabaco significativamente mayor que aquellos con afecciones oculares más leves.
Conclusiones:
- Fumar está fuertemente asociado con la presencia de la oftalmopatía de Graves.
- El aumento del consumo de tabaco se correlaciona con la gravedad de las manifestaciones oculares en la enfermedad de Graves.
- Se debe recomendar encarecidamente dejar de fumar a los pacientes con enfermedad de Graves, especialmente a aquellos con o en riesgo de oftalmopatía.
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