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Colorimetric Assessment of Deiodinase 1 Activity in Human Liver Microsomes Using the Sandell-Kolthoff Reaction
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Sitio de unión al sustrato inhibidor de la indoleamina humana 2,3-dioxigenasa

Changyuan Lu1, Yu Lin, Syun-Ru Yeh

  • 1Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

Journal of the American Chemical Society
|September 10, 2009
PubMed
Resumen

La indoleamina 2,3-dioxigenasa humana (hIDO) tiene un sitio de sustrato inhibidor recientemente identificado. Este hallazgo ayuda en el desarrollo de nuevas inmunoterapias contra el cáncer y la reevaluación del agente antitumoral Mitomycin C.

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