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Updated: Jun 19, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

Las estructuras cristalinas del cisplatino unidas a una chaperona de cobre humano

Amie K Boal1, Amy C Rosenzweig

  • 1Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA.

Journal of the American Chemical Society
|October 8, 2009
PubMed
Resumen

Las proteínas de tráfico de cobre como Atox1 son clave para la resistencia al cisplatino. Las estructuras cristalinas muestran que el cisplatino se une a Atox1, revelando mecanismos para la resistencia a los medicamentos contra el cáncer.

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