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Updated: Jun 19, 2026

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

Un tándem de ciclización en cascada y sustitución aromática electrofílica: aplicación en la síntesis total de (+) -

Joseph J Topczewski1, Michael P Callahan, Jeffrey D Neighbors

  • 1Department of Chemistry, University of Iowa, Iowa City, Iowa 52242-1294, USA.

Journal of the American Chemical Society
|October 15, 2009
PubMed
Resumen

Se desarrolló una nueva reacción en tándem que implica la apertura del epoxido y la sustitución aromática electrofílica. Este método permitió la primera síntesis del producto natural (+) -angelicalcona.

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