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Mirando hacia arriba nuevos jugadores Wnt Pathway Wnt.
1Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands. h.clevers@hubrecht.eu
Cell
|October 20, 2009
Resumen
La vía de señalización Wnt es crucial para el desarrollo y la reparación de tejidos. Una nueva investigación revela cómo un complejo ligando-receptor Wnt específico influye en el desarrollo vascular y la enfermedad de la retina.
Área de la Ciencia:
- Biología del desarrollo Biología del desarrollo.
- La señalización celular de las células.
- Oftalmología Oftalmología.
Sus antecedentes:
- La vía de señalización Wnt regula los procesos celulares fundamentales, incluida la determinación del destino celular, la proliferación y la diferenciación.
- La desregulación de la señalización Wnt está implicada en varias anomalías y enfermedades del desarrollo.
- El desarrollo vascular de la retina es crítico para la visión y es susceptible a diversas enfermedades.
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