Finales: los últimos minutos de Smads

Ye-Guang Chen1, Xiao-Fan Wang

  • 1State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Tsinghua University, Beijing 100084, China. ygchen@tsinghua.edu.cn

Cell
|November 17, 2009
PubMed
Resumen

La transformación de la señalización del factor de crecimiento beta (TGF-β) implica la fosforilación de la proteína Smad. Esta fosforilación del enlace es crucial tanto para la activación de Smad como para la posterior degradación, revelando una doble función reguladora.

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