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RNAi: los procariotas se meten en el acto.
John van der Oost1, Stan J J Brouns
1Laboratory of Microbiology, Wageningen University, 6703 HB Wageningen, Netherlands. john.vanderoost@wur.nl
Cell
|December 1, 2009
Resumen
Los sistemas CRISPR-Cas ofrecen inmunidad adaptativa en los microbios. Una nueva variante en Pyrococcus furiosus se dirige al ARN, no al ADN, expandiendo las funciones conocidas de estos mecanismos de defensa.
Área de la Ciencia:
- Microbiología Microbiología.
- Biología Molecular Biología Molecular
- Genética La genética.
Sus antecedentes:
- Los sistemas CRISPR-Cas son mecanismos inmunológicos adaptativos de los procariotas.
- Estos sistemas suelen dirigirse al ADN extraño utilizando ARN derivados de CRISPR.
- Las investigaciones anteriores se centraron en la orientación del ADN por las proteínas asociadas a CRISPR (Cas).
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