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Updated: Jun 17, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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Reacciones de Mannich enantioselectivas catalizadas por carbenos N-heterocíclicos con alfa-ariloxiacetaldehídos

Yasufumi Kawanaka1, Eric M Phillips, Karl A Scheidt

  • 1Department of Chemistry, Center for Molecular Innovation and Drug Discovery, Chemistry of Life Processes Institute, Silverman Hall, Northwestern University, Evanston, Illinois 60208, USA.

Journal of the American Chemical Society
|December 17, 2009
PubMed
Resumen

Los carbenos N-Heterocíclicos (NHCs) catalizan una nueva reacción de tipo Mannich, produciendo derivados enantioselectivos de ácido beta-amino. Este concepto de catálisis de carbenos ofrece una síntesis eficiente de valiosos compuestos basados en aminoácidos.

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