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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

Anulación [3 + 2] catalizada por el rodio de los indolos

Yajing Lian1, Huw M L Davies

  • 1Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, USA.

Journal of the American Chemical Society
|December 23, 2009
PubMed
Resumen

Una nueva reacción catalizada por el rodio crea ciclopentanulación de los anillos indoliles con alta precisión. Este método permite la generación de dos productos regioisoméricos distintos, mostrando avances significativos en la síntesis asimétrica.

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