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MicroTUB(B3)ules y el desarrollo del cerebro
1Howard Hughes Medical Institute, Cambridge, MA 02139, USA.
Cell
|January 21, 2010
Resumen
Las mutaciones en el gen TUBB3 interrumpen el desarrollo neuronal al afectar la dinámica de los microtúbulos. Esto impacta la migración de las neuronas y causa varios síntomas de enfermedades neurológicas.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- Biología celular Biología celular.
- Genética La genética.
Sus antecedentes:
- La red de microtúbulos es esencial para el desarrollo y la función neuronal.
- Se sabe que las mutaciones en los genes que codifican la tubulina perjudican la migración neuronal.
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