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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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El acoplamiento cruzado Suzuki estereospecífico de los triflados de alquilo alfa-cianohidrina

Anyu He1, J R Falck

  • 1Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Journal of the American Chemical Society
|February 4, 2010
PubMed
Resumen

Los triflados escalemicos de alfa-cianohidrina se pueden acoplar con ácidos borónicos utilizando la catálisis del paladio. Esta reacción procede con la inversión de la configuración, dando nitriles complejos para futuras transformaciones sintéticas.

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