El alcohol de patchouli de doble etiqueta de deuterio procedente de la ciclización del difosfato de farnesilo de

Juan A Faraldos1, Shuiqin Wu, Joe Chappell

  • 1Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, USA.

Resumen

Este estudio revela cómo la patchoulol sintasa (PTS) crea el patchoulol utilizando farnesil difosfato etiquetado con deuterio. La investigación aclara el mecanismo de la enzima, identificando un cambio de 1,3-hidruro y un nuevo intermedio.

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