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Updated: Jun 16, 2026

A High Content Imaging Assay for Identification of Botulinum Neurotoxin Inhibitors
14:10

A High Content Imaging Assay for Identification of Botulinum Neurotoxin Inhibitors

Published on: November 14, 2014

Neurotoxina botulínica proteasa A: descubrimiento de inhibidores de exositos de productos naturales

Peter Silhár1, Katerina Capková, Nicholas T Salzameda

  • 1Department of Chemistry, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|February 18, 2010
PubMed
Resumen

Los compuestos naturales de la equinácea, como el ácido d-chicórico, inhiben la metaloproteasa de zinc de la neurotoxina botulínica tipo A (BoNT/A). Estos inhibidores de la equinácea ofrecen una nueva clase mecanicista para el potencial desarrollo terapéutico.

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