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The Mechanics of (Poro-)Elastic Contractile Actomyosin Networks As a Model System of the Cell Cytoskeleton08:50

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In this work, an in vitro reconstitution approach is employed to study the poroelasticity of actomyosin gels under controlled conditions. The dynamics of the actomyosin gel and the embedded solvent are quantified, through which the network poroelasticity is demonstrated. We also discuss the experimental challenges, common pitfalls, and relevance to cell cytoskeleton...
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Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix09:13

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This protocol presents a method to perform rheology characterization of mucus that resides on gill rakers (GRs) of the silver carp. Viscoelastic characteristics of GR-mucus, obtained by measuring viscosity, storage and loss moduli, are evaluated for the apparent yield stress to understand the filter feeding mechanism in...
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The Diffusion of Passive Tracers in Laminar Shear Flow08:01

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A protocol for the study of the diffusion of passive tracers in laminar pressure-driven flow is presented. The procedure is applicable to various capillary pipe...
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Two different methods for characterizing the incipient particle motion of a single bead as a function of the sediment bed geometry from laminar to turbulent flow are...
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An experimentally accessible analog method for studying molecular hydrodynamic processes in dense fluids is presented. The technique uses particle image velocimetry of vibrated, high-restitution grain piles and allows direct, macroscopic observation of dynamical processes known and predicted to exist in strongly interacting, high density gases and...
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Confocal microscopy is used to image quiescent and flowing colloid-polymer mixtures, which are studied as model systems for attractive suspensions. Image analysis algorithms are used to calculate structural and dynamic metrics for the colloidal particles that measure changes due to geometric...
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Video Experimental Relacionado

Updated: Jan 12, 2026

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix
09:13

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix

Published on: July 10, 2020

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La coevolución antagónica acelera la evolución molecular.

Steve Paterson1, Tom Vogwill, Angus Buckling

  • 1School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK.

Nature
|February 26, 2010
PubMed
Resumen
Este resumen es generado por máquina.

La coevolución antagónica entre especies, como anfitriones y parásitos, acelera la evolución molecular. Este estudio demuestra empíricamente que el fago coevolucionante evolucionó más rápido y mostró una mayor divergencia genética que aquellos con huéspedes constantes.

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An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids
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Videos de Experimentos Relacionados

Last Updated: Jan 12, 2026

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Área de la Ciencia:

  • Biología evolutiva Biología evolutiva.
  • La genómica microbiana es la genómica microbiana.
  • Las dinámicas de la coevolución.

Sus antecedentes:

  • La hipótesis de la Reina Roja postula que las especies deben adaptarse y contra-adaptarse continuamente para sobrevivir.
  • La evidencia empírica para la hipótesis de la Reina Roja ha sido limitada debido a las largas escalas de tiempo requeridas para los estudios coevolucionarios.

Objetivo del estudio:

  • Para poner a prueba empíricamente la hipótesis de la Reina Roja mediante el examen de las tasas de evolución molecular en sistemas coevolucionantes huésped-parásito.
  • Investigar el impacto de la coevolución antagónica en la velocidad y el patrón de la evolución molecular en un sistema de bacterias y fagos.

Principales métodos:

  • Evolución experimental utilizando poblaciones de Pseudomonas fluorescens SBW25 y su fago Phi2.2.
  • Comparación de las tasas de evolución molecular de los fagos que evolucionan con un huésped coevolucionante frente a un genotipo de huésped constante.
  • Analizando la divergencia genética y el rango de infección del huésped de las poblaciones de fagos evolucionados.

Principales resultados:

  • Las tasas de evolución molecular de los fagos fueron significativamente más altas cuando coevolucionaron con la bacteria en comparación con la evolución contra un huésped constante.
  • La coevolución condujo a una mayor divergencia genética entre las poblaciones de fagos replicados.
  • El grado de divergencia genética se correlacionó con el rango de huéspedes que el fago coevolucionado podría infectar.
  • Los genes involucrados en la infección del huésped mostraron la evolución más rápida bajo la presión coevolucionaria.

Conclusiones:

  • La coevolución antagonista es un motor significativo de la evolución molecular rápida y divergente tanto a nivel genómico como fenotípico.
  • Este estudio proporciona apoyo empírico directo a la hipótesis de la Reina Roja en un sistema microbiano.
  • Las dinámicas coevolucionarias son cruciales para comprender el cambio evolutivo dentro de las especies.