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Los nacidos muertos relacionados con la infección
Robert L Goldenberg1, Elizabeth M McClure, Sarah Saleem
1Drexel University College of Medicine, Philadelphia, PA 19102, USA. rgoldenb@drexelmed.edu
Lancet (London, England)
|March 13, 2010
Resumen
Las infecciones causan una parte significativa de los mortinatos en todo el mundo, particularmente en las naciones de bajos ingresos. Las estrategias dirigidas a infecciones específicas como la sífilis y la malaria son cruciales para la prevención de la muerte fetal.
Área de la Ciencia:
- Obstetricia y Ginecología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Salud global La salud global.
Sus antecedentes:
- La infección es una de las principales causas de muerte fetal en todo el mundo, con una mayor prevalencia en los países de ingresos bajos y medios (LMIC) en comparación con los países de ingresos altos.
- La sífilis es uno de los principales contribuyentes a los mortinatos infecciosos y es susceptible de detección y tratamiento.
- Otras causas infecciosas importantes incluyen infecciones bacterianas ascendentes, infecciones virales, malaria y enfermedades zoonóticas.
Objetivo del estudio:
- Para resaltar el impacto global de las infecciones en las tasas de mortinatos.
- Para identificar agentes infecciosos específicos y factores de riesgo asociados con el nacimiento de un bebé muerto.
- Hacer hincapié en la necesidad de estrategias de prevención específicas, especialmente en los LMIC.
Principales métodos:
- El estudio es una revisión de la literatura existente sobre infección y muerte fetal.
- Sintetiza datos sobre la prevalencia y el impacto de varias infecciones en las tasas de mortinatos a nivel mundial.
- Se discuten las estrategias de prevención actuales y potenciales para los mortinatos infecciosos.
Principales resultados:
- En los LMIC, es probable que las infecciones causen el 50% o más de los mortinatos, frente al 10-25% en los países de altos ingresos.
- La sífilis es la causa infecciosa más común susceptible de intervención.
- La malaria y las infecciones bacterianas ascendentes también son contribuyentes significativos.
Conclusiones:
- Reducir los nacimientos muertos a nivel mundial requiere estrategias efectivas para prevenir y controlar las infecciones.
- Las intervenciones específicas para la sífilis, la malaria y otras infecciones prevalentes son esenciales.
- Se necesita más investigación para desarrollar e implementar estrategias efectivas de prevención de las infecciones zoonóticas y transmitidas por vectores en los PIMC.
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