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Updated: Jun 14, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

Quiral bis (imidazolidina) piridina-Cu (OTf) 2: cicloadición catalítica asimétrica endoselectiva [3 + 2] de ésteres

Takayoshi Arai1, Asami Mishiro, Naota Yokoyama

  • 1Department of Chemistry, Graduate School of Science, Chiba University, Inage, Chiba 263-8522, Japan. tarai@faculty.chiba-u.jp

Journal of the American Chemical Society
|March 30, 2010
PubMed
Resumen

Se desarrolló un nuevo catalizador quiral, PyBidine-Cu (((OTf) ((2), para la síntesis asimétrica. Este catalizador promueve eficientemente reacciones altamente endo-selectivas, produciendo productos con hasta un 99% de exceso enantiomérico.

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