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Updated: Jun 14, 2026

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Catálisis de una hidrólisis de amida mediada por una flavoenzima

Tathagata Mukherjee1, Yang Zhang, Sameh Abdelwahed

  • 1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA.

Journal of the American Chemical Society
|April 8, 2010
PubMed
Resumen

Los investigadores descubrieron una nueva flavoenzima, RutA, que inicia la vía catabólica de la pirimidina en E. coli mediante la oxidación del uracil. Este hallazgo revela un mecanismo oxidativo único para la apertura del anillo, destacando el cofactor flavin.

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