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IkappaBzeta regula el desarrollo de T(H) 17 cooperando con los receptores nucleares ROR

Kazuo Okamoto1, Yoshiko Iwai, Masatsugu Oh-Hora

  • 1Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.

Nature
|April 13, 2010
PubMed
Resumen

Un nuevo factor de transcripción, IkappaBzeta, es crucial para el desarrollo de las células T auxiliares (T (H) 17) productoras de Interleucina-17. Este descubrimiento ofrece nuevas estrategias terapéuticas para enfermedades autoinmunes como la encefalomielitis autoinmune experimental (EAE).

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