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Updated: Jun 13, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

Una vía de tres enzimas para la formación y incorporación de 2-amino-3-hidroxiciclopent-2-enona en la biosíntesis de

Wenjun Zhang1, Megan L Bolla, Daniel Kahne

  • 1Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|April 17, 2010
PubMed
Resumen

Los investigadores identificaron una vía de tres enzimas en Streptomyces aizunenesis para la formación del anillo C(5) N, un componente clave en productos naturales como la moenomicina. Esta vía involucra enzimas específicas para la condensación, la ciclización y la ligadura de amida, ofreciendo información sobre la biosíntesis de productos naturales.

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