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Una vía de biosíntesis para BE-7585A, un producto natural de tipo angucíclina que contiene 2-tiosugar y que contiene

Eita Sasaki1, Yasushi Ogasawara, Hung-Wen Liu

  • 1Division of Medicinal Chemistry, College of Pharmacy, and Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA.

Journal of the American Chemical Society
|May 7, 2010
PubMed
Resumen

Los investigadores investigaron la biosíntesis de BE-7585A, un compuesto que contiene un raro 2-tiosugar. Identificaron el grupo de genes bex y una enzima clave, BexG2, crucial para la síntesis del precursor del 2-tiosugar, allanando el camino para futuros estudios.

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