Video Experimental Relacionado
Updated: Jul 31, 2026
10:05
A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
Published on: May 7, 2017
Potencial de la corteza visual para desarrollar una serie de unidades funcionales únicas de la corteza
1Molecular Neurobiology Laboratory, Salk Institute, La Jolla, CA 92037.
Science (New York, N.Y.)
|June 14, 1991
Resumen
El desarrollo neocortical muestra plasticidad. La corteza visual embrionaria trasplantada desarrolló "barrillas" somatosensoriales, lo que indica potenciales de diferenciación similares en todas las regiones del cerebro.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- Biología del desarrollo Biología del desarrollo.
- La neuroanatomía es la neuroanatomía.
Sus antecedentes:
- Las áreas especializadas en el neocórtex de los mamíferos, como la corteza visual y somatosensorial, están definidas por características arquitectónicas y funcionales únicas.
- Comprender si estas características distintas están predeterminadas o influenciadas por interacciones epigenéticas es crucial para comprender el desarrollo neocortical.
Objetivo del estudio:
- Investigar el potencial de desarrollo de las áreas neocorticales examinando si las características de un área pueden surgir en otra.
- Para determinar en qué medida las características específicas de la zona neocortical están prespecificadas o epigenéticamente determinadas.
Principales métodos:
- Trasplante de la corteza visual embrionaria tardía en la corteza somatosensorial neonatal de las ratas.
- Análisis histológico y molecular del tejido trasplantado para identificar "barrillas" y límites asociados de glucoconjugados.
Principales resultados:
- La corteza visual trasplantada desarrolló con éxito "barrillas" y sus límites característicos de glucoconjugados.
- Estas estructuras formaban una matriz organizada, imitando el patrón observado en el campo de tiro de la corteza somatosensorial nativa.
Conclusiones:
- Las regiones neocorticales en desarrollo poseen potenciales latentes similares para diferenciar características características de distintas áreas corticales.
- Los factores epigenéticos y el entorno local juegan un papel importante en la configuración de la organización funcional de la neocórtex, en lugar de la estricta predeterminación genética por sí sola.
Videos de Conceptos Relacionados
01:24Vision
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
01:33Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
01:14Motor and Sensory Areas of the Cortex
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
01:21Association Areas of the Cortex
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
01:11Sensory Perception: Organization of the Somatosensory System
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
01:23Somatosensory, Motor, and Association Cortex
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at the...