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Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays
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Un punto de control esencial del desarrollo para la producción del linaje de células T

Tomokatsu Ikawa1, Satoshi Hirose, Kyoko Masuda

  • 1Laboratory for Lymphocyte Development, RIKEN Research Center for Allergy and Immunology, Yokohama 230-0045, Japan.

Science (New York, N.Y.)
|July 3, 2010
PubMed
Resumen

Los investigadores identificaron el primer punto de control en el desarrollo de las células T. Los niveles reducidos de interleucina-7 promueven la determinación del linaje de células T, que depende del factor de transcripción Bcl11b.

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