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El Flipping MLL1 cambia una prolina a la vez

Edward J Grow¹, Joanna Wysocka

¹Department of Genetics, Stanford University, Stanford, CA 94305, USA.

|July 7, 2010

Resumen

La proteína del linaje mixto leucemia 1 (MLL1) regula los genes Hox en el desarrollo de la sangre. Una proteína llamada ciclofilina CyP33 cambia MLL1

Área de la Ciencia:

Biología molecular La biología molecular.
La hematopoyesis es la hematopoyesis.
La epigenética es la epigenética.

Sus antecedentes:

La proteína de la leucemia de linaje mixto 1 (MLL1) juega un papel crucial en la regulación de la expresión del gen Hox durante la hematopoyesis.
Las alteraciones en MLL1 se observan con frecuencia en varias formas de leucemia.

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