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La señalización de TGF-beta especifica los axones durante el desarrollo cerebral

Jason J Yi1, Anthony P Barnes, Randal Hand

  • 1Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.

Cell
|July 7, 2010
PubMed
Resumen

El factor de crecimiento transformador beta (TGF-beta) actúa como una señal extracelular para establecer la polaridad neuronal, guiando a las neuritas a convertirse en axones en el cerebro en desarrollo de los mamíferos. Este descubrimiento revela un factor clave en el patrón de los circuitos neuronales.

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