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Bases estructurales para la neutralización amplia y potente del VIH-1 por el anticuerpo VRC01

Tongqing Zhou1, Ivelin Georgiev, Xueling Wu

  • 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|July 10, 2010
PubMed
Resumen

El anticuerpo ampliamente neutralizante VRC01 se dirige a la envoltura gp120 del virus de la inmunodeficiencia humana (VIH). Su mecanismo de unión único, que imita la interacción del receptor CD4, supera las defensas virales para una neutralización efectiva del VIH-1.

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