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Updated: Jun 10, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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Published on: February 16, 2018

Mutagénesis dirigida por el sitio estructuralmente informada de una aldoasa estereocímicamente promiscua para

Sylvain F Royer1, Luke Haslett, Susan J Crennell

  • 1Centre for Extremophile Research, Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom BA2 7AY.

Journal of the American Chemical Society
|August 6, 2010
PubMed
Resumen

Los investigadores diseñaron una enzima aldolasa termostable de Sulfolobus solfataricus para mejorar el control estereocímico en la formación de enlaces carbono-carbono. Este trabajo mejora la producción de isómeros específicos de D-2-ceto-3-deoxygluconato (D-KDGlu) y D-2-ceto-3-deoxy-galactonato (D-KDGal).

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