Síntesis de 3-trifluorometilbenzo[b]furanos a partir de fenoles a través de la ortofuncionalización directa mediante

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Updated: Jun 10, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
08:43

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Published on: January 19, 2016

Takayuki Kobatake1, Daishi Fujino, Suguru Yoshida

  • 1Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

Journal of the American Chemical Society
|August 7, 2010
PubMed
Resumen

Un nuevo método sintetiza de manera eficiente los trifluorometilbenzo[b]furanos a partir de los fenoles. Este enfoque utiliza reacciones de Pummerer mediadas por anhídrido trifílico, lo que permite la formación de diversos productos a través de modificaciones posteriores del grupo metiltio.

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