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La proteína priónica como receptor para el beta amiloide

Helmut W Kessels1, Louis N Nguyen, Sadegh Nabavi

  • 1Center for Neural Circuits and Behavior, 9500 Gilman Drive 0634, University of California at San Diego, La Jolla, California 92093, USA.

Nature
|August 13, 2010
PubMed
Resumen

Este estudio muestra que la proteína priónica celular (PrP(C)) no es necesaria para que el beta amiloide cause defectos sinápticos en modelos de la enfermedad de Alzheimer. La amiloide-beta perjudica la función cerebral independientemente de la PrP.

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