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Updated: Jun 10, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

Pd(II) - catalizado por la activación C-H dirigida por hidroxilo/ciclización de CO: construcción expediente de

Xisheng Wang1, Yi Lu, Hui-Xiong Dai

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|August 19, 2010
PubMed
Resumen

Una nueva reacción catalizada por el paladio permite la síntesis de dihidrobenzofuranos a través de la activación de C-H y la ciclización de C-O. Este método es útil para crear moléculas complejas, incluidas estructuras espirocíclicas, con aplicaciones potenciales en la síntesis de productos naturales.

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