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La reversión de la caquexia
1Nutritional Biomedicine, School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK. m.j.tisdale@aston.ac.uk
Cell
|August 21, 2010
Resumen
La caquexia por cáncer, una afección potencialmente mortal, puede tratarse mediante el bloqueo del receptor de activina de tipo 2 (ActRIIB). Este enfoque revirtió el desgaste muscular y aumentó la vida útil en modelos de ratón, ofreciendo nuevas esperanzas terapéuticas.
Área de la Ciencia:
- Oncología Oncología.
- Fisiología Muscular Fisiología Muscular
- Biología Molecular Biología Molecular
Sus antecedentes:
- La caquexia por cáncer es una afección grave con opciones de tratamiento limitadas.
- El desgaste muscular afecta a los músculos esqueléticos y cardíacos, lo que afecta la supervivencia del paciente.
- La identificación de nuevos objetivos terapéuticos para la caquexia es crucial.
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