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Desimetrización de las imidas mesocíclicas a través de la monohidrogenación enantioselectiva

Satoshi Takebayashi1, Jeremy M John, Steven H Bergens

  • 1Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2G2.

Journal of the American Chemical Society
|August 26, 2010
PubMed
Resumen

Las imidas cíclicas quirales se someten a hidrogenación asimétrica para crear hidroxilactamas con alta enantioselectividad utilizando catalizadores de rutenio. Esta reacción de desimetrización genera eficientemente múltiples estereocentros, lo que permite la síntesis de moléculas complejas.

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