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Síntesis total de (+) -corupensamina B a través de un acoplamiento atropselectivo intermolecular de biarilo

Shenlin Huang1, Tue B Petersen, Bruce H Lipshutz

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.

Journal of the American Chemical Society
|September 21, 2010
PubMed
Resumen

Los investigadores informan de la primera síntesis total asimétrica de la korupensamina B. no racémica. Este logro utiliza una nueva ruta hacia el núcleo de tetrahidroisoquinolina y un innovador acoplamiento atropdiastereoselectivo Suzuki-Miyaura.

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