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Updated: Jun 8, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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Published on: February 16, 2018

Bromolactonización asimétrica mediante el uso de un catalizador de amino-tiocarbamato

Ling Zhou1, Chong Kiat Tan, Xiaojian Jiang

  • 1Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

Journal of the American Chemical Society
|October 16, 2010
PubMed
Resumen

Un nuevo método catalítico permite la síntesis eficiente de gamma-lactonas a partir de ácidos carboxílicos insaturados. Esta bromolactonización catalizada por amino-tiocarbamato logra altos rendimientos y enantioselectividad, lo que resulta útil en la síntesis de fármacos intermedios.

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