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Videos de Conceptos Relacionados

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the generated carbocation,...
Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
Anionic Chain-Growth Polymerization: Mechanism01:04

Anionic Chain-Growth Polymerization: Mechanism

The mechanism for anionic chain-growth polymerization involves initiation, propagation, and termination steps. In the initiation step, a nucleophilic anion, such as butyl lithium, initiates the polymerization process by attacking the π bond of the vinylic monomer. As a result, a carbanion, stabilized by the electron‐withdrawing group, is generated. The resulting carbanion acts as a Michael donor in the propagation step and attacks the second vinylic monomer, which acts as a Michael acceptor.

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Updated: Jun 7, 2026

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
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Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers

Published on: December 16, 2022

El polisacárido ácido imita a través de la polimerización de la metástasis de apertura de anillos.

Michel Wathier1, Stephanie S Stoddart, Matthew J Sheehy

  • 1Department of Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, Massachusetts 02215, United States.

Journal of the American Chemical Society
|October 23, 2010
PubMed
Resumen

Los investigadores desarrollaron un nuevo método para crear polímeros hidrófilos de alto peso molecular con ácido carboxílico y grupos hidroxilo. Estos polímeros parecidos a los carbohidratos se muestran prometedores como sustitutos sintéticos de polisacáridos en biotecnología y farmacia.

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Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
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Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
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Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
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Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
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Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

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Área de la Ciencia:

  • Química de Polímeros La Química de Polímeros es la química de los polímeros.
  • Ciencia de los materiales Ciencia de los materiales.
  • Biotecnología La biotecnología es la biotecnología.

Sus antecedentes:

  • Los polímeros hidrófilos con diversos grupos funcionales son cruciales para las aplicaciones biomédicas.
  • Imitar los polisacáridos naturales como el alginato es un objetivo clave en el diseño de polímeros sintéticos.

Objetivo del estudio:

  • Desarrollar una estrategia sintética eficiente y general para polímeros hidrofílicos de alto peso molecular.
  • Para crear polímeros con ácido carboxílico y grupos colgantes hidroxilo.
  • Para explorar aplicaciones como sustitutos de polisacáridos sintéticos.

Principales métodos:

  • La polimerización de la metatesis de apertura de anillo (ROMP) del metil 5-oxanorborneno-2-carboxilato mediante el catalizador Grubbs II.
  • Modificación posterior a la polimerización para introducir funcionalidades de hidroxilo o ácido carboxílico.
  • Caracterización del peso molecular del polímero (∼100.000 a 5.000.000 g/mol).

Principales resultados:

  • Se ha sintetizado con éxito poli (ácido carboxílico 5,6-dihidroxioxano o borborano) con altos pesos moleculares.
  • Afinación demostrada de propiedades hidrofóbicas/hidrofílicas a través de la introducción de grupos funcionales.
  • Formación de hidrogeles con polilisina, imitando el comportamiento del alginato.

Conclusiones:

  • La estrategia sintética descrita es eficiente y general para producir polímeros hidrófilos funcionales.
  • Estos polímeros similares a los carbohidratos son valiosos para los estudios de la relación estructura-propiedad.
  • Los polímeros ofrecen potencial como nuevos sustitutos de polisacáridos sintéticos en biotecnología y productos farmacéuticos.