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Differentiation of Common Myeloid Progenitor Cells01:15

Differentiation of Common Myeloid Progenitor Cells

Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
Antigen Presenting Cells01:22

Antigen Presenting Cells

The immune system is a complex network of cells and molecules that protects the body from foreign invaders. T cells, a type of white blood cell, play a crucial role in this process. They recognize and attack foreign substances, such as pathogens, that enter the body.
T cells require the help of antigen-presenting cells (APCs), which process foreign antigens into smaller fragments that can be recognized by T cells. These APCs are highly specialized cells that efficiently internalize antigens...
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

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Lineage Commitment01:21

Lineage Commitment

Commitment is the  process whereby stem cells:

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Video Experimental Relacionado

Updated: Jun 7, 2026

Generation of Human Monocyte-derived Dendritic Cells from Whole Blood
07:35

Generation of Human Monocyte-derived Dendritic Cells from Whole Blood

Published on: December 24, 2016

Los monocitos se unen a la familia de células dendríticas.

Federica Sallusto1, Antonio Lanzavecchia

  • 1Institute for Research in Biomedicine, Bellinzona, Switzerland. federica.sallusto@irb.unisi.ch

Cell
|October 30, 2010
PubMed
Resumen

Las células dendríticas son células inmunes clave. En respuesta a la infección bacteriana, los monocitos se convierten rápidamente en células dendríticas en los ganglios linfáticos para presentar antígenos a las células T.

Área de la Ciencia:

  • Inmunología Inmunología.
  • Biología celular Biología celular.

Sus antecedentes:

  • Las células dendríticas (DC) son células presentadoras de antígenos (APC) cruciales que unen la inmunidad innata y la inmunidad adaptativa.

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Generation of Human Monocyte-derived Dendritic Cells from Whole Blood
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Characterization of Human Monocyte-derived Dendritic Cells by Imaging Flow Cytometry: A Comparison between Two Monocyte Isolation Protocols
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  • Los CD juegan un papel vital en el inicio de las respuestas inmunes y el mantenimiento de la auto-tolerancia.