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Mortalidad pediátrica relacionada con la infección por influenza pandémica A H1N1 en Inglaterra: un estudio
Nabihah Sachedina1, Liam J Donaldson
1Department of Health, London, UK.
Lancet (London, England)
|October 30, 2010
Resumen
La pandemia de influenza A H1N1 causó una mortalidad infantil significativa, particularmente en bebés y en ciertos grupos étnicos minoritarios. La vacunación y la atención temprana son cruciales para los niños de alto riesgo para prevenir resultados graves.
Área de la Ciencia:
- Epidemiología La epidemiología.
- Salud Pública La salud pública.
- Enfermedades infecciosas Enfermedades infecciosas.
Sus antecedentes:
- La pandemia de influenza A H1N1 afectó desproporcionadamente a los jóvenes.
- El análisis de la mortalidad pediátrica es vital para la preparación para futuras pandemias.
Objetivo del estudio:
- Para analizar la mortalidad pediátrica asociada con la influenza pandémica A H1N1.1.
- Informar las políticas clínicas y de salud pública para futuras temporadas de influenza.
Principales métodos:
- Análisis retrospectivo de las muertes pediátricas en Inglaterra (junio 2009-marzo 2010).
- Datos recopilados a través de informes diarios, comprobación cruzada de registros y confirmación de laboratorio / certificado de defunción.
- La población y las tasas de mortalidad fueron las principales medidas de resultado.
Principales resultados:
- Se reportaron 70 muertes pediátricas, con una tasa de mortalidad infantil de 6 por millón.
- Los bebés (<1 año) y los niños de grupos étnicos de Bangladesh y Pakistán se enfrentaron a tasas de mortalidad más altas.
- Trastornos preexistentes graves, especialmente enfermedades neurológicas crónicas, mayor riesgo de mortalidad; el 21% de los niños fallecidos eran previamente sanos.
Conclusiones:
- La prioridad de vacunación debe dirigirse a los niños con alto riesgo de enfermedad severa o muerte por influenza.
- Los grupos de alto riesgo incluyen aquellos con trastornos específicos preexistentes y ciertas minorías étnicas.
- La atención temprana pre-hospitalaria de apoyo y terapéutica es esencial para mejorar los resultados.
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