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Highly Resolved Intravital Striped-illumination Microscopy of Germinal Centers
Published on: April 10, 2014
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Brillando una luz sobre el centro germinal de las células B
1Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA. jason.cyster@ucsf.edu
Cell
|November 16, 2010
Resumen
La selección de células B en los tejidos linfoides se aclara utilizando proteínas fotoactivadas. La maduración de la afinidad de anticuerpos es impulsada por las células B que compiten por la ayuda de las células T.
Área de la Ciencia:
- Inmunología Inmunología.
- Biología celular Biología celular.
- Biología Molecular Biología Molecular
Sus antecedentes:
- Los mecanismos de la selección de células B en los tejidos linfoides siguen sin estar claros.
- Comprender la selección de células B es crucial para la respuesta inmune.
- La dinámica del centro germinal influye en la inmunidad adaptativa.
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