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El control motor por la corteza sensorial
Ferenc Matyas1, Varun Sreenivasan, Fred Marbach
1Laboratory of Sensory Processing, Brain Mind Institute, Faculty of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Science (New York, N.Y.)
|November 27, 2010
Resumen
Los investigadores descubrieron una vía directa de control motor desde la corteza somatosensorial primaria (S1) hasta los movimientos de los bigotes en ratones. Esta vía retrae rápidamente los bigotes, ofreciendo una nueva perspectiva sobre la integración sensorimotora y la organización cortical.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- El control del motor es el control del motor.
- Los sistemas sensoriales son sistemas sensoriales.
Sus antecedentes:
- Tradicionalmente se ha reconocido que la corteza motora primaria controla el movimiento de los mamíferos.
- El sistema de bigotes en ratones es un modelo clave para el estudio de la integración sensorimotora.
Objetivo del estudio:
- Investigar vías corticales alternativas para el control motor más allá de la corteza motora primaria.
- Para aclarar el papel de la corteza somatosensorial primaria en los comportamientos sensoriales activos como el whisking.
Principales métodos:
- Registros electrofisiológicos en ratones.
- Análisis conductual de los movimientos de los bigotes.
- La manipulación causal de la actividad neuronal en las córtices sensorial y motor.
Principales resultados:
- Identificó una vía directa desde la corteza somatosensorial primaria hasta el control motor de los bigotes.
- Demostró que la actividad primaria de la corteza somatosensorial impulsa directamente la retracción del bigote.
- Se demostró que la actividad de la corteza motora primaria impulsa directamente la prolongación del bigote.
Conclusiones:
- La corteza somatosensorial primaria juega un papel directo y significativo en el control motor de los bigotes.
- Esta vía motora impulsada por los sentidos proporciona una rápida retroalimentación negativa para la integración sensoriomotriz.
- Los hallazgos requieren una reevaluación de la organización funcional de los mapas corticales y los circuitos de control del motor.
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