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Updated: May 7, 2026
09:30
Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms
Published on: September 13, 2018
Consecuencias del mal funcionamiento del armario de ARNm
Carol J Wilusz1, Jeffrey Wilusz
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, 80523, USA.
Cell
|December 15, 2010
Resumen
Las partículas de ribonucleoproteínas mensajeras (mRNP) son esenciales para la expresión génica. Una nueva investigación muestra que la remodelación de estos complejos de ARNm-proteína también es crucial para la degradación del ARNm.
Área de la Ciencia:
- Biología Molecular Biología Molecular
- Regulación de la expresión génica Regulación de la expresión génica
Sus antecedentes:
- Las moléculas de ARN mensajero (ARNm) se asocian con las proteínas para formar partículas de ribonucleoproteína mensajera (mRNP) poco después de la transcripción.
- Estos mRNP experimentan una remodelación dinámica a lo largo de varias etapas de la expresión génica, incluida la traducción y la localización.
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