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Assessing Autophagic Flux by Measuring LC3, p62, and LAMP1 Co-localization Using Multispectral Imaging Flow Cytometry
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Assessing Autophagic Flux by Measuring LC3, p62, and LAMP1 Co-localization Using Multispectral Imaging Flow Cytometry

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La autofagia en la inmunidad y la inflamación.

Beth Levine1, Noboru Mizushima, Herbert W Virgin

  • 1Department of Microbiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9113, USA. beth.levine@utsouthwestern.edu

Nature
|January 21, 2011
PubMed
Resumen

La autofagia, un proceso celular, es vital para la adaptación a la escasez de nutrientes y la inmunidad. Las proteínas de la autofagia regulan las respuestas celulares a la infección, la inflamación y pueden proteger contra enfermedades relacionadas.

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