Modelado a nivel atómico de la cápside del VIH

Owen Pornillos1, Barbie K Ganser-Pornillos, Mark Yeager

  • 1Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

Nature
|January 21, 2011
PubMed
Resumen

Los investigadores determinaron la estructura de rayos X del pentámero del virus de la inmunodeficiencia humana tipo 1 (VIH-1), revelando reordenamientos sutiles y un interruptor electrostático que controla el ensamblaje de la cápside. Este trabajo permite el modelado a nivel atómico de la cápside completa del VIH-1.

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